Side-effects
dry mouth, appetite changes, gastro-intestinal disturbances (including nausea, diarrhoea, constipation, and dyspepsia), abdominal pain; tachycardia, vasodilatation, chest pain, palpitation; headache (uncommonly migraine), anxiety, sleep disturbances, dizziness, drowsiness, depression, confusion, paraesthesia, asthenia; visual disturbances; less commonly flatulence, reflux, vomiting, mouth ulcers, glossitis, dysphagia, taste disturbance, weight changes, hypertension, hypotension, bradycardia, arrhythmia, peripheral oedema, hypercholesterolaemia, rhinitis, dyspnoea, epistaxis, dyskinesia, amnesia, emotional lability, tremor, decreased libido, agitation, aggression, hyperglycaemia, thirst, urinary frequency, menstrual disturbances, eosinophilia, leucopenia, myasthenia, muscle cramps, hypertonia, myalgia, arthralgia, dry eye, sinusitis, acne, sweating, rash, and pruritus; also reported psychosis, mania, delusions, hallucinations, suicidal ideation, Stevens-Johnson syndrome, and toxic epidermal necrolysis

Dose
Narcolepsy and obstructive sleep apnoea syndrome, adult over 12 years, initially 200 mg daily, either in 2 divided doses morning and at noon or as a single dose in the morning, dose adjusted according to response to 200–400 mg daily in 2 divided doses or as a single dose; elderly initiate at 100 mg daily; child 5–12 years, see BNF for Children

Chronic shift work sleep disorder, 200 mg taken 1 hour before the start of the work shift

What about the dosage?Nobody mentions it!

Medical student

I’m using the drug for what It’s intended for – to increase your alertness during waking hours, not to fool your brain into thinking that it doesn’t need to sleep for days on end. I can imagine using it to fuel an all nighter would be worth it – but you’d probably need to catch up on the lost sleep the next night.

I’d also like to say that I think it was a risky experiment to do without medical supervision or consultation beforehand.

Disclosure: Biochemistry student with interest in pharmacodynamics

Anyone who stays awake for days on end will suffer adverse effects.
The only side effect I notice is that while there is no “buzz”, there can be a slight hangover effect – I sometimes get a dull headache as it wears off in the evening.

Lisalot – I recommend you ask your doctor, I also recommend you give it a try.

I disagree you could stay up all night and feel great. You feel rough (belive me!). I tried it, and you still feel awful; awake but awful.

If you keep taking this drug, but trying to sleep as normal, you find rem sleep stolen off you each night. as time goes by, even when trying to sleep normally, the reduced rem begins to catch up with you. You’ll know this when you appear to sleep but feel rough in the morning.

I would reccommend this drug for short stints of high output work, so long as you stick to your sleep and eating routines. But I feel using it to stay up all night is an assult on your body. I would highly reccommend against it!

I swap between concerta and this drug for control of my ADHD symptoms, so that I can work more productively in a subject that is extremely difficult for someone without ADHD.

As someone who has bought higher concentration drugs over the internet than required, because they were less than half the price from this particular web pharmacy than the other extortionate pharmacies, I’m used to cutting pills in half very carefully with a razor sharp knife.

I’m guessing that many people are like me in wanting the waking effects but certainly not wanting to be kept awake well into sleep time. There’s a time for exam cramming and that time doesn’t bear any resemblance to the rest of life. Incidentally, I did something like the big cramming described at the end of a long course- in fact not far from twice the 60 hours with about 2 hours sleep per night. Without anything but proplus and sometimes some coffee. Very hard and I nearly didn’t do it and nearly didn’t graduate at all probably! Because I remembered nearly nothing about the subject!!! before this emergency last minute stuff.